Traditional Chinese medicine on four patients with Huntington's disease
Identifieur interne : 002014 ( Main/Exploration ); précédent : 002013; suivant : 002015Traditional Chinese medicine on four patients with Huntington's disease
Auteurs : Takashi Satoh [Japon] ; Toshiyuki Takahashi [Japon] ; Koh Iwasaki [Japon] ; Hideaki Tago [Japon] ; Takashi Seki [Japon] ; Nobuo Yaegashi [Japon] ; Muneshige Tobita [Japon] ; Hiroyuki Arai [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-02-15.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Chinese, Chorea, Cross-Over Studies, Drugs, Chinese Herbal (therapeutic use), Female, Human, Humans, Huntington Disease (genetics), Huntington disease, Huntington's disease, Medicine, Chinese Traditional (methods), Middle Aged, Nervous system diseases, Pilot Projects, Yi‐Gan San (yokukansan), chorea, movement disorder, traditional Chinese medicine.
- MESH :
- chemical , therapeutic use : Drugs, Chinese Herbal.
- genetics : Huntington Disease.
- methods : Medicine, Chinese Traditional.
- Aged, Cross-Over Studies, Female, Humans, Middle Aged, Pilot Projects.
Abstract
Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi‐Gan San (YGS) and Chaihu‐Jia‐Longgu‐Muli Tan (CLMT) in a cross‐over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale—motor assessment (from 106.3 ± 4.7 to 89.6 ± 5.8 as mean ± SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22447
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi‐Gan San (YGS) and Chaihu‐Jia‐Longgu‐Muli Tan (CLMT) in a cross‐over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale—motor assessment (from 106.3 ± 4.7 to 89.6 ± 5.8 as mean ± SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements. © 2009 Movement Disorder Society</div>
</front>
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<name sortKey="Arai, Hiroyuki" sort="Arai, Hiroyuki" uniqKey="Arai H" first="Hiroyuki" last="Arai">Hiroyuki Arai</name>
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<name sortKey="Iwasaki, Koh" sort="Iwasaki, Koh" uniqKey="Iwasaki K" first="Koh" last="Iwasaki">Koh Iwasaki</name>
<name sortKey="Seki, Takashi" sort="Seki, Takashi" uniqKey="Seki T" first="Takashi" last="Seki">Takashi Seki</name>
<name sortKey="Tago, Hideaki" sort="Tago, Hideaki" uniqKey="Tago H" first="Hideaki" last="Tago">Hideaki Tago</name>
<name sortKey="Takahashi, Toshiyuki" sort="Takahashi, Toshiyuki" uniqKey="Takahashi T" first="Toshiyuki" last="Takahashi">Toshiyuki Takahashi</name>
<name sortKey="Takahashi, Toshiyuki" sort="Takahashi, Toshiyuki" uniqKey="Takahashi T" first="Toshiyuki" last="Takahashi">Toshiyuki Takahashi</name>
<name sortKey="Tobita, Muneshige" sort="Tobita, Muneshige" uniqKey="Tobita M" first="Muneshige" last="Tobita">Muneshige Tobita</name>
<name sortKey="Yaegashi, Nobuo" sort="Yaegashi, Nobuo" uniqKey="Yaegashi N" first="Nobuo" last="Yaegashi">Nobuo Yaegashi</name>
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