Movement Disorders (revue)

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Traditional Chinese medicine on four patients with Huntington's disease

Identifieur interne : 002014 ( Main/Exploration ); précédent : 002013; suivant : 002015

Traditional Chinese medicine on four patients with Huntington's disease

Auteurs : Takashi Satoh [Japon] ; Toshiyuki Takahashi [Japon] ; Koh Iwasaki [Japon] ; Hideaki Tago [Japon] ; Takashi Seki [Japon] ; Nobuo Yaegashi [Japon] ; Muneshige Tobita [Japon] ; Hiroyuki Arai [Japon]

Source :

RBID : ISTEX:D1DA50C14F6EA3AD941D7D6310CF49D82C8D1491

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English descriptors

Abstract

Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi‐Gan San (YGS) and Chaihu‐Jia‐Longgu‐Muli Tan (CLMT) in a cross‐over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale—motor assessment (from 106.3 ± 4.7 to 89.6 ± 5.8 as mean ± SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements. © 2009 Movement Disorder Society

Url:
DOI: 10.1002/mds.22447


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi‐Gan San (YGS) and Chaihu‐Jia‐Longgu‐Muli Tan (CLMT) in a cross‐over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale—motor assessment (from 106.3 ± 4.7 to 89.6 ± 5.8 as mean ± SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements. © 2009 Movement Disorder Society</div>
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